Is it reasonable to treat with RT alone for limited stage SCLC if unable to receive chemotherapy?
If there is hilar LN involvement only, could you consider hypofractionated RT?
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To what dose would you treat limited stage SCLC if treating with daily RT alone, with no adjuvant systemic therapy planned?
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2 Answers
Mednet MemberInvited Expert
Radiation Oncology · Memorial Sloan Kettering Cancer Center
Answered on
Yes, I think this is reasonable, though obviously expectations should be tempered, as SCLC is essentially a systemic disease and as such, RT alone should be viewed as palliative treatment or aimed at preventing imminent morbidity from local progression. I would consider a hypofractionated regimen su...
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Mednet Member
Radiation Oncology · Gadsden Regional Medical Center
Answered on
Since standard of care is BID treatment (45Gy in 30 fractions), that may be a reasonable option. And a recent abstract suggests a benefit with escalating BID to 60Gy (in 40 fractions), And therefore it would be reasonable to go to this higher dose given that the patient will not be receiving chemo. ...
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