Is it safe to give spine SBRT after recent cryoablation?

How would you treat a patient that had a T10 lytic lesion with extension to posterior 10th rib s/p cryoablation of the rib 4 months ago, but with residual disease at the pedicle and body of T10?

What dose/fractionation would you recommend?

Answer from: Radiation Oncologist at Academic Institution

There is a small randomized trial (CROME) of SBRT vs Cryo + SBRT open at MD Anderson addressing this question. In this trial, SBRT is done within a few weeks of cryotx. The trial is still accruing and results are not available. In lieu of randomized data, I think it would be reasonable to consider S...

Comments

Radiation Oncologist at Mon Health
Would you consider 9 Gy x 3 equally effective?

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