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Is local failure following SABR higher then previously thought?

ASTRO 2014's lung session presented data from RTOG 0236, showing a 20% intralobar failure/recurrence despite only 7% local failure. How does one reconcile this information with local control rates reported in other SABR trials?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · University of Texas Southwestern Medical Center
Answered on

The problem really surrounds the common practice of sloppy reporting of patterns of failure in clinical reports. Local failure is failure within the realm of the original T-stage definitions. For lung cancer, failure within the lobe is a local failure. Too many SABR reports have only included failur...

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