Is Oncotype testing useful in variant histologies such as micropapillary breast cancer?
2 Answers
Mednet MemberInvited Expert
Medical Oncology · Icahn School of Medicine at Mount Sinai
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I have no idea whether Oncotype testing is predictive of benefit to chemotherapy in micropapillary breast cancer, which is a rare variant. Micropapillary variant tends to worse prognosis and greater degree of nodal positivity in some studies. However, in other studies, the prognosis is similar to in...
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Mednet MemberInvited Expert
Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida
Answered on
Agree with Dr. @Dr. First Last. There is a SEER based Oncotype score study (using preTAILORx cutoffs) by Wang et al., PMID 30619463 that included about 270 micropapillary cases along with IDC, ILC, and other special subtypes like mucinous and tubular. The micropapillary cases had similar percentage ...
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