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Is SBRT an option for a paravertebral lung cancer with vertebral body and rib invasion for patients who are not chemo candidates?

What is your level of concern for chest wall toxicity? Any difference in your thought process between SCLC vs. NSCLC?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Cleveland Clinic
Answered on

I do believe SBRT is an option for paravertebral lung cancer with VB and rib invasion. My rationale is that SBRT offers improved local control and cancer outcome compared to conventionally fractionated radiation - and that while there may be potential for increased toxicity of treatment in this scenario that the favorable return of improved tumor control (particularly for disease in a critical/symptomatic location) outweighs/balances the potential for increased toxicity. The exact SBRT dosing (typically we have used 50 Gy in 5 fractions every other day) or use of alternative hypofractionated SBRT-like regimens such as 60/8, 60/15, 70/10 would be determined by the anatomy and planning of the particular case. These doses are assuming this is ...

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