Topics:
Radiation Oncology • Thoracic Malignancies
Is the presence of carcinoma in situ at the staple line after lobectomy completed for invasive disease an indication for PORT?
What if there was a pT1aN0 invasive adenocarcinoma that was separate from the focus of adenocarcinoma in situ which resulted in the positive margin. The literature reflects that there is no difference in survival between those with negative margins and those with R1 resection attributable to CIS. However, many of those patients received PORT.
Answer from: Radiation Oncologist at Academic Institution
Usually not, in my opinion. Not all CIS will progress to become invasive disease, and in many patients the pace of any progression will be slower than competing comorbidities (or even other areas of CIS). The typical situation is that the radiographic mass is resected, and the CIS has no...
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