Is the presence of ubiquitin-specific peptidase 8 (USP8) genotype helpful in determining the risk of Cushing disease recurrence?

Indeed, a recent retrospective, multicenter, international study (published in Lancet DM) reported that patients with USP8-variant tumors are more likely to experience recurrence of Cushing's disease in comparison with patients with microadenomas that are USP8-wildtype (37% vs. 15% at 10 yr). On the...