Topics:
Radiation Oncology • Pediatric Oncology
Is there a benefit to metastatic & primary site RT in RMS w/ persistent marrow disease?
In a patient with high risk rhabdomyosarcoma with significant marrow involvement (Stage IV), who has responded completely on imaging to all known sites after chemo, would you proceed with planned XRT if re-staging bone marrow biopsy still showed rare malignant cells?
Answer from: Radiation Oncologist at Academic Institution
I would treat the primary site based on it likely having the greatest concentration if not burden of disease. However, if for some reason the patient has had a resection with +microscipic margins, then I would be much more hesitant to do local therapy since the burden of disease in that circum...
I would echo the above. We know that there is a mo...