Is there a field size in which you would consider single fraction palliative radiation unsafe?

For example, is 8 Gy x 1 well tolerated in the setting of multi-level vertebral body radiation?

Answer from: Radiation Oncologist at Community Practice

There is nothing to suggest a larger field size when treating multiple body levels increases the risk of complications with 8 Gy single fraction. Radiobiologically it is less dose to cord than 30 Gy in 10 fractions. We routinely use it. Only if a large GI volume gets treated small bowel or sto...

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