Is there a role for bevacizimab (IV or IA) for steroid refractory radionecrosis for AVM?
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Would you feel comfortable using bevacizumab for a patient with radiation necrosis following SRS treatment of an AVM?
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2 Answers
Mednet MemberInvited Expert
Radiation Oncology · University of Arizona
Answered on
Radiation necrosis (RN) following SRS can occur at variable intervals of time following treatment, usually occurring 9-18 months later. The preferred first line of approach is usually steroids, as done in this case. I usually look at the MRI-Flair images and determine the dose of dexamethasone depen...
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Mednet Member
Radiation Oncology · Yale Cancer Center At Smilow Cancer Hospital
Answered on
Agree with the above. In addition, I would suggest considering other alternatives to treating radionecrosis that may have more favorable side effect profiles and may (purely conjecture) be able to treat the underlying cause of radionecrosis (inflammation) as opposed to just mitigating its symptoms a...
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