Is there a role for chronic suppressive oral or inhaled therapy for recurrent Burkholderia cepacia pneumonia causing frequent hospitalizations in a patient with severe bronchiectasis with or without underlying cystic fibrosis?

In certain cases, certainly, suppression may be the optimal role but in conjunction with modification to the immunosuppression. Generally, the immunosuppression will need to be lowered to allow for cellular immunity to combat the infection. Other factors include whether the gemovar is a more aggress...

The answer is yes; thinking outside of transplant, CF or not CF, this tends to be a serious gram-negative bacteria with some caveats on genomovar about how virulent they can be; however, if they cause frequent exacerbations, then chronic suppression can be considered to prevent them; what to use is ...

These people are usually chronically ill with underlying copd lifestyle challenges, improving with good nutrition, and avoiding immuno-suppressants, complement the colonization of these bugs.