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Is there a role for cinacalcet in the management of PTHrP-mediated hypercalcemia?

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Would you use cinacalcet in the management of PTHrP-mediated hypercalcemia?

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1 Answer
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Endocrinology · Boston University School of Medicine
Answered on · Updated on

Cinacalcet is a calcimimetic, meaning that it mimics calcium and interacts with the calcium sensor in the parathyroid glands, which is a signal to decrease the production of PTH. Cinacalcet will not decrease the production of PTHRP in cancer cells. However, cinacalcet will decrease the production of...

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