Is there a role for cinacalcet in the management of PTHrP-mediated hypercalcemia?
1 Answers
Mednet Member
Endocrinology · Boston University School of Medicine
Cinacalcet is a calcimimetic, meaning that it mimics calcium and interacts with the calcium sensor in the parathyroid glands, which is a signal to decrease the production of PTH. Cinacalcet will not decrease the production of PTHRP in cancer cells. However, cinacalcet will decrease the production of...