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Is there a role for measuring serum mycophenolate mofetil levels (or its active metabolite) in the management of lupus nephritis?

1 Answer
Mednet MemberInvited Expert
Rheumatology · Hackensack University Medical Center
Answered on

I check MMF levels in 2 different scenarios:

  1. It helps improve adherence. If levels are undetectable, this provided an opportunity to discuss adherence with patients and to identify barriers to taking MMF more regularly without skipping doses.
  2. For patients with CKD/ESRD who are on low MMF doses and may need higher MMF doses to achieve symptoms control, very low levels make me less concerned about increasing MMF.

I do not use MMF levels to adjust MMF doses in general.

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