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Is there a role for progestin therapy to temporize bleeding from endometrial cancer in a patient with an active venous thromboembolism?

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What progestin(s) might you consider using to temporize bleeding from endometrial cancer in a patient with an active venous thromboembolism?

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1 Answer
Mednet MemberInvited Expert
Gynecologic Oncology · Froedtert Hospital, Medical College of Wisconsin
Answered on

In the setting of a newly diagnosed DVT in an otherwise surgically appropriate patient with known endometrial cancer, I would still consider keeping with the standard strategy of proceeding with surgical staging. I would place a filter and proceed with minimally invasive approach, if feasible. Postoperatively, anticoagulation could resume after 24-48 hours if no evidence of bleeding. If not a surgical candidate then would need to proceed to definitive radiation therapy and in that situation, als...

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