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Is there a role for radiation in biphenotypic sinonasal sarcoma?

Biphenotypic sinonasal sarcoma is a recently described malignancy showing dual differentiation with both myogenic and neural elements.
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · NYC Health + Hospitals
Answered on

It’s a sarcoma, so there may be a role in the neoadjuvant or adjuvant setting. Not for definitive therapy, however. Surgery is the mainstay of definitive management of sarcoma.  

If there’s no surgical option then you can consider out-of-the-box approaches with SBRT or hypofractionation, or even brachytherapy — it would depend on the anatomical site, tumor size and stage, and patient factors. If you are able to share more case details, I can provide a more specific answer.