Is there a role for the use of SGLT2 inhibitors for the treatment of reactive hypoglycemia not responsive to dietary modifications or acarbose?  

I would be concerned and very cautious about using SGLT2 inhibitors for "Reactive hypoglycemia." This type of hypoglycemia is a form of hyperinsulinemic hypoglycemia, sometimes associated with late dumping syndrome in those who have had gastric bypass or fundoplication surgery or those who have...

Only sotagliflozin may help because it also inhibits SGLT1 which inhibits glucose absorption in the intestines. Increasing urinary glucose loss would be too late to prevent the rapid rise in blood glucose which stimulates insulin release. Adding corn starch to meals also provides delayed glucose ...