Is there an age cutoff over which you would not recommend definitive radiation for intermediate risk prostate cancer?

In general, I prefer to try to evaluate a patient's physiological age rather than merely use chronological age as an absolute cut off for definitive radiation. Thus, both performance status and co-morbidities factor heavily into my decision whether or not to recommend definitive radiation. In addition, an individual's disease characteristics influence my recommendation. The distinction between favorable and unfavorable intermediate risk groups becomes especially important when age is a factor. The available data would suggest that the prognosis for favorable intermediate risk patients is very similar to that of low risk patients, and for an elderly patient with significant commorbities who falls into this category, I might be more inclined ...