Is there an eGFR or urine output rate for which you would no longer recommend pre- and post-hydration for a patient with AKI who requires liposomal amphotericin B?

I'm not aware of any data to guide recommendations on this. Since it is a simple measure, I err on the side of caution and (barring overt volume overload) recommend hydration in any patient with AKI receiving ampho B, regardless of eGFR and urine output.