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Is there any benefit to changing a monoclonal EGFR inhibitor therapy when one had to be stopped for cutaneous toxicity?

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Mednet Member
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Medical Oncology · Rutgers Cancer Institute of New Jersey
Answered on

The two anti-EGFR monoclonals both have high rates of cutaneous toxicity. It isn't clear that one is better than the other, so switching Is not a good option. It is better to reduce the dose and treat through with doxycycline and steroids. Generally the rash will improve within 4-6 weeks. In the cas...

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