Is there any benefit to transplant patients with Ph+ ALL who have achieved MRD-negativity?

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Are you still GENERALLY recommending allogeneic transplantation for adults with Ph+ ALL in first remission?

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1 Answer

Mednet MemberInvited Expert

Medical Oncology · University of Washington

Answered on

First, some semantics: Asking if there is a "benefit to transplant" may imply there are randomized controlled trials addressing this question, but none to my knowledge have been performed. The last "donor-no donor" trials done in adults with ALL in first remission largely occurred in the pre-TKI era...

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