Is there any evidence for amyloid/amyloidosis causing a spurious/false PSA reading?
This is an excellent question.
Our group has been involved with amyloid/radiation effects in patients with Alzheimer’s disease
Turn our initial run-up and through our most recent reviews, I have not seen any significant publications nor have I seen clinical situations that this addresses, although amyloid has very interesting effects in the body.
I would caution, however, that we have eight patients that we are following who developed COVID-19 and then were noted to have increasing PSA. Each of these patients has undergone at least one saturation biopsy, and then none of the cases was recurrent tumor identified.
We continue to monitor these patients.
But back to the amyloid question, if there is a noted increase in the PSA and if a PSMA scan...
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