Is there any evidence for combining surgery and XRT +/- ADT for treatment of localized high risk prostate cancer?

Presumably, this is a question inquiring about planned post-operative RT. If so, surgery followed by adjuvant, post-operative radiation therapy (PORT) has been profiled extensively in several RCTs: EORTC 22911, SWOG 8794, ARO 96-02, FinnProstataX. The two more recent trials, ARO 96-02 and FinnProstataX, are most representative of the benefit of pure adjuvant radiotherapy, given that each required an undetectable/low PSA for their main analysis (≤ 0.1 and < 0.5, respectively). In these trials, a ...