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Is there any evidence that ivermectin suppresses the PSA level in prostate cancer?

I had two prostate cancer patients recently take ivermectin against medical advice. Both of them had their PSA drop by 2-3 ng/ml. Are you seeing this in practice? Patients taking ivermectin on their own and then their PSAs drop? Of course, there is concern about toxicity of ivermectin, especially liver toxicity.
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Radiation Oncology · UC San Diego
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Is this even the right question, though? ADT drops PSA very reliably and yet does not cure patients. Finasteride suppresses PSA, but we do not use it as a mainstay of cancer treatment. Even if ivermectin *did* suppress PSA, unless there is a meaningful oncologic benefit (*at least* reduced recurrenc...

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Medical Oncology · Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty
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Is there any evidence that ivermectin suppresses the PSA level in prostate cancer?

Short answer: No. There is no evidence in the medical literature that ivermectin suppresses prostate-specific antigen (PSA) levels in prostate cancer. Current evidence is limited to preclinical models, and there are no...

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Radiation Oncology · Cancer Treatment Group
Answered on

I have a patient who had a PSA response to self-administered ivermectin and fenbendazole.

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