Is there any indication for obtaining adrenal imaging in patients with MEN2 who have normal plasma or urinary metanephrines?

Excellent question.

Patients with pheochromocytoma-paraganglioma can present with intermittent catecholamine production.

It is important to measure metabolites (O-methylated metabolites) based on work by Eisenhofer et al., PMID 15644397: intratumor metabolism of catecholamines to free metanephrines.

P...