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Is there any role for early stem cell mobilization and collection during the SMM phase?

Do you worry about the ability to collect stem cells (at the time of progression to MM) if someone with SMM has been on prolonged lenalidomide?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · Harvard Medical School
Answered on

Prolonged exposure to lenalidomide can affect the ability to mobilize and collect stem cells, though this is less of an issue with increasing use of plerixafor (Giralt et al., 2009). If you are going to treat with an IMD, it is important to collect stem cells after 4-6 months of therapy, similar to ...

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