Is there data to support worse surgical outcomes in short course RT followed by surgery vs. long course chemoradiation followed by surgery in rectal cancer?
Additionally, is there a difference in surgical outcomes with long course chemoradiation + consolidative chemo vs. induction chemo + long course chemoradiation?
2 Answers
Mednet Member
Radiation Oncology · Mallory Radiotherapy, PLLC
Answered on
This question seems to be asking about surgical outcomes between short and long course radiation in both TNT and non-TNT approaches. With regards to the latter, the TROG 01.04 trial compared pre-operative short course RT to long course chemoRT. There was no difference in OS, LC, late toxicity, or su...
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Mednet MemberInvited Expert
Radiation Oncology · University of Florida
Answered on
Not to my knowledge
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