Is there evidence of clinical benefit to proceeding with partial pleurectomy / decortication over palliative chemotherapy with BSC (pleurex catheter, pleurodesis) in a patient with mesothelioma who is not a candidate for extra-pleural pneumectomy?
What factors influence your decisions to offer neoadjuvant chemotherapy?
Answer from: Medical Oncologist at Academic Institution
There is no compelling evidence here. The only randomized data are from the UK MesoVATS trial, reported in 2014, showed that patients with pleural mesothelioma randomized to video-assisted thoracoscopic partial pleurectomy/decortication had no difference in 1 year survival compared to those who und...
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