Is there evidence that radiation therapy can cause a flare in cancer antigens or other biomarkers?
There is some data that suggests PSA and EBV can flare early in radiation therapy treatment courses in prostate and nasopharyngeal patients, respectively. Is there evidence flare of cancer antigens or biomarkers with radiation with in other cancers, such as an increase in CA 19-9 during radiation for cholangiocarcinomas?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on
I have noticed with limited experience and elevation of CA 125 during RT for localized recurrent ovarian cancer which has settled down to normal after completion of RT. Could be because of release of antigen caused by tumor breakdown.
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