J Am Acad Dermatol 2020 Sep 04
Accuracy of commercial panels to evaluate myositis autoantibodies: A single-institution perspective.
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What is your approach to elevated CK in patients without clinical or serologic evidence of immune mediated myopathy?
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1 Answers
Mednet Member
Rheumatology · Emory University
Thanks for your great question: This is especially important because we are much more likely to see patients sent for "elevated" CPK than patients with myositis.Unfortunately, I think that the answer to the approach depends a lot the circumstances, including (1) how elevated is the CPK, and (2) how ...
What is the negative predictive value of a negative extended myositis panel in dermatomyositis patients?
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2 AnswersMednet Member
Rheumatology · Emory University
The short answer is "not great, but it depends" since the more nuanced answer is contingent on: the constellation of myositis-specific antibodies (MSA) included on the panel, the nitty-gritty of how the commercial lab is checking the MSA included (this detail can change between vendors, or even ...