Annals of oncology : official journal of the European Society for Medical Oncology 2022 Mar 14

Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study.

Related Questions

What adjuvant systemic therapy would you give a patient with pN2 nodal relapse of ER+/HER2- breast cancer now s/p ALND, after initial mastectomy, adjuvant TC, and 5 years of endocrine therapy?

I'll give my thoughts, but appreciate others here as well. I'm assuming this patient is likely now post-menopausal, and also assuming that they had 5 years of endocrine therapy and then relapsed off of adjuvant therapy.I'm guessing the patient did not have radiation as they had a mastectomy and did ...

What endocrine therapy would you recommend to a premenopausal female with early stage HR+ Breast cancer who is transitioning from female to male and currently on testosterone?

1 Answers

Mednet Member

Medical Oncology · Mayo Clinic College of Medicine and Science

There is not a lot of data, and so shared decision-making is paramount, with the following considerations: Acknowledging the limited data in this setting, how would this patient feel about stopping testosterone? While many patients feel that T is critical for identity, others may not feel that way. ...