Blinatumomab for MRD-Negative Acute Lymphoblastic Leukemia in Adults.

N Engl J Med 2024 Jul 25

Related Questions

In patients with Philadelphia-negative ALL who are transplant ineligible, is there any data to guide the duration of maintenance POMP therapy?

Does your approach change if the MRD is negative post-blinatumomab?

Would you recommend an allogenic stem cell transplant in an older patient > 50 with Ph negative acute lymphoblastic leukemia who is MRD negative after induction?

Does your answer change based on clinical or molecular risk factors, and if so how? Does your answer change if MRD status after induction is unknown?

New answer by Medical Oncologist at University of Washington (October 19, 2025)

In general, I would not routinely recommend allogeneic hematopoietic cell transplantation (HCT) for Ph- acute lymphoblastic leukemia (ALL) that is in MRD-negative remission th...

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