PFS curves appear similar between the AKT-altered vs overall study population in the trial publication. Is there any additional information available ...
New answer by Medical Oncologist at Mary Lanning Healthcare Morrison Cancer Center/University of Nebraska Medical Center Adjunct Faculty (March 23, 2024)
In the presence of preclinical data showing inhibition of growth by capivasertib in some cell lines without AKT pathway gene alterations (Davies et al., PMID 22294718) and the...