Gynecol Oncol 2017 Aug
Isolated tumor cells identified by sentinel lymph node mapping in endometrial cancer: Does adjuvant treatment matter?
Related Questions
How would you manage an elderly but otherwise healthy patient with a high grade endometrioid uterine cancer with micro metastasis to a SLN, but otherwise confined to the uterus with superficial myometrial invasion?
With sentinel lymph nodes, pathology can show isolated tumor cells, micro metastasis, or macro metastasis. Our tumor board definitely has debated on how to handle micro metastasis in any patient, but especially those that are elderly, have treatment limited by social determinants, or have to travel ...
Would you recommend radiation for micrometastasis on sentinel lymph node biopsy in otherwise low risk endometrial cancer?
This is a great question! There really isn’t great data on what should be done with micrometastasis. At our tumor board, there is a clear consensus to treat macrometastasis on sentinel nodes. There is also a clear consensus that while we are capturing data to monitor our outcomes with isolated tumor...
Do you offer pelvic radiation for endometrial cancer with ITCs in the node(s) and no other high or intermediate risk factors?
This is an uncertain area with limited outcome data. Ultrastaging with SNLN is picking up more ITC of which the clinical significance is unclear and may result in overtreatment. The data suggests ITCs have much better outcomes then micro or macromets but possible inferior outcome to node negative di...