Pharmacogenetics, cost of genotyping, and guidelines for individualizing therapy with mercaptopurine in pediatric acute lymphoblastic leukemia.

Mednet Member

Pediatric Hematology/Oncology · Emory University

My practice is to send a pharmacogenetic panel that includes TPMT and NUDT15 (as well as some other useful tidbits such as UGT1A! for Gilbert's syndrome) when patients with ALL are diagnosed. The cost-effectiveness of this strategy has been addressed, with different conclusions (van den Akker-van Ma...