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Transfusion 2020 Sep 24

Sickle cell anemia and COVID-19: Use of voxelotor to avoid transfusion.

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Is there experience/reports of using voxelotor in sickle cell patients who are Jehovah Witnesses with few crises but who have fatigue and/or dyspnea?

1 Answers
Mednet Member
Mednet Member
Hematology · Boston University School of Medicine

I would not hesitate to use voxelotor in most patients with sickle cell anemia, including Jehovah's Witnesses, if they have not responded to hydroxyurea with near cessation of acute vasoocclusive events and have continued hemolytic anemia. Voxelotor usually reduces hemolysis that results in an incre...