The Complexity of Managing Large Brain Metastasis.

Mednet MemberInvited Expert

Radiation Oncology · Columbia University Irving Medical Center

For large intact brain metastases, my preferred fSRS dose/fractionation would be 27 Gy in 3 daily fractions. There are retrospective studies showing 1-yr local control rates of 91% using 27 Gy in 3 daily fractions vs 77% using single fraction SRS for large intact brain metastases > 2 cm (Minniti et ...