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Should a different weight-based dosing algorithm for levothyroxine therapy be considered in women versus men given higher incidence of iatrogenic thyrotoxicosis in women?

Adams & Mammen, PMID 40117123
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Do you use a different weight-based dosing algorithm for levothyroxine therapy in women compared to men, given the higher incidence of iatrogenic thyrotoxicosis in women?

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1 Answer
Mednet Member
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Endocrinology · Emory University School of Medicine
Answered on

I do not.

For the majority of my patients, my starting dose is 1.6 mcg/kg, which is in the ATA guidelines (1.6-1.8 mcg/kg has been recommended as the starting dose in many publications). There have been some studies that show using ideal body weight is a better predictor of LT4 dose, and others tha...

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