Should aTTR mutation with bilateral carpal tunnel alone prompt treatment with a gene silencing drug?

Carpal Tunnel Syndrome does not qualify as a peripheral neuropathy due to TTR amyloid. The amyloid deposition is in the soft and/or connective tissue and not in the nerve. As such, there is no clear indication to treat as much as one might be tempted. Careful follow-up and treatment as soon as neuro...