Should breast cancer patients with never-treated latent TB and for whom chemotherapy is indicated be treated for latent TB during chemotherapy?

Topics: Breast Cancer • Medical Oncology • NCI-CCC Tumor Board Question • UCLA

Answer from: Medical Oncologist at Community Practice

Interestingly latent tb reactivation while on cyclic combination Chemotherapy is quite rare even in endemic countries like India, including among patients treated for leukemia. This could be due to cyclic nature of immune suppression rather than chronic immune suppression which is required for tb re...

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Medical Oncologist at University of Iowa Holden Comprehensive Cancer Center
Combination chemotherapy alone is not considered h...

Answer from: Medical Oncologist at Academic Institution

Considering the concern that immunosuppression from chemotherapy could lead to reactivation of TB, I would be in favor of treating latent TB while a patient is receiving chemotherapy.

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