Should chemoradiotherapy to primary and neck be offered to patients with Stage IVC nasopharyngeal carcinoma with limited osseous disease?
What are the data for loco-regional and distant recurrence rates with and without local therapy? What is the OS advantage?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Medical University of South Carolina (Charleston)
Answered on
Yes. Please refer to the recent small phase III randomized trial: You et al., PMID 32701129.
Anecdotally, I have treated an Asian patient with EBV-associated NPC who had a single sternal met at presentation with definitive chemoxrt (no induction) who is is ~7 years post treatment and is NED.
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