Should household contacts of Haemophilus influenza invasive disease patients be given immediate antibiotic prophylaxis?  

Since the use of conjugated Hib vaccine in 1987, invasive type B disease is quite rare, and in my adult population, unheard of. 

When I see an adult hospitalized with Haemophilus influenzae growth from sputum or blood culture, it creates much anxiety to immediately prophylax all household members, not a small consideration when there is a large household and rifampin requires a review of each person's entire medication list.   Prescribing rifampin for 4 days can cause GI side effects as well.

CDC data 2015 - 2019* states an incidence of invasive B disease 3 cases / 10 million population.

Given these statistics, Is it reasonable to wait until the immunotyping result is available before prescribing rifampin to an entire household?

Reference:

*Current Epidemiology and Trends in Invasive Haemophilus influenzae Disease—United States, 2009–2015.  Soeters, Heidi M. Clin Infect Dis. 67(6):881-889

URL : https://stacks.cdc.gov/view/cdc/59723