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Should olaparib maintenance therapy be recommended in patients with BRCA-positive, advanced ovarian cancer after first line platinum-based chemotherapy?

Should this be the new standard of care based on the results from the recently published SOLO-1 trial?
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Do you use Olaparib maintenance therapy in patients with BRCA-positive, advanced ovarian cancer after first line platinum-based chemotherapy?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Medical Oncology · The Ohio State University Comprehensive Cancer Center
Answered on

While the results of the SOLO-1 trial are initially impressive, we need to wait for the survival data and the results of the other 2 European trials (Paola-1 and ENGOT). Definitively a field of research to keep an eye on. Today, probably premature. On a case by case basis, might be acceptable, but n...

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