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Should special precautions be taken when treating oligometastatic disease in the sacrum or pelvis with SBRT in a patient with a long life expectancy?

For example in a patient with a good performance status and a biologically favorable cancer (ER+ breast cancer, EGFR+ NSCLC, or prostate cancer), are you worried about increased fracture risk over time? What dose fractionation would you consider?
1 Answer
Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Mayo Clinic
Answered on

There's so much good data now that if you can work it out (insurance, etc) it's worth doing. My suggestion is to do it, but paint within the lines, meaning don't use a dose that's poorly studied and 1) adhere to good quality dose constraints like TG101, and 2) consider the PTV coverage...in that ord...

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