Should testing for Lyme disease be a routine part of work-up for new-onset high-degree AV block prior to PPM implantation, regardless of patient age or exposure history?

Lyme testing cannot be relied upon in all clinical circumstances because there is an appreciable rate of false positive results. Not only is there cross-reactivity with other infections, but the antibody tests may remain positive for years after an infection has resolved. There can also be false neg...