Should we routinely incorporate iron studies into admissions for acute decompensated heart failure?

Low serum Iron level in ADHF patients is an independent predictor of poor prognosis. Iron is an essential element in oxygen transportation, delivery, and utilization. I would check the Iron panel in patients with ADHF. However, the frequency of follow-up has not been well defined. Iron deficiency is one of the frequent co-morbidities noted in ADHF patients (both HFrEF & HFpEF) and is a predictor of heart failure outcomes. Some patients have absolute deficiency and some have functional deficiency. Although there is no significant CV mortality benefit, reduction in HF readmissions is noted with IV iron replacement. AFFIRM-AHF and PRACTICE-ASIA-HF reviewed the benefit of IV iron supplementation in patients with ADHF and ID.