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Statistically speaking, approximately what percentage of thyroid nodule FNA biopsies are Bethesda category 1 (= nondiagnostic or unsatisfactory), and what percentage are indeterminate (Bethesda category 3 and 4)?

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Endocrinology · Boston University Geriatric Services
Answered on

This is highly institution-specific, but on average:

  • About 10% of biopsies will be nondiagnostic.
  • About 15-30% of biopsies will be indeterminate (Bethesda 3 or 4).

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