Mednet Logo

Under what circumstances would you consider reirradiation for a patient with recurrent previously irradiated early stage laryngeal cancer now s/p salvage laryngectomy?

Would you treat all cases or only select risk factors (T4, N+/ECE, margin+, LVI etc.)? What would you treat? Would a negative neck diseection change your recommendations?
1 Answer
Mednet Member
Mednet Member
Radiation Oncology · Michigan Healthcare Professionals, PC
Answered on

This type of patient would have been allowable on the GETUG trial which randomized patients after surgical salvage to no further treatment or re-irradiation with chemotherapy. The study showed a DFS advantage, but no OS advantage. There were more deaths due to treatment in the treatment arm (5 vs 0)...

Join for free or sign in to see the full answer