Topics:
Head and Neck Cancers • Radiation Oncology
Under what circumstances would you consider reirradiation for a patient with recurrent previously irradiated early stage laryngeal cancer now s/p salvage laryngectomy?
Would you treat all cases or only select risk factors (T4, N+/ECE, margin+, LVI etc.)? What would you treat? Would a negative neck diseection change your recommendations?
Answer from: Radiation Oncologist at Community Practice
This type of patient would have been allowable on the GETUG trial which randomized patients after surgical salvage to no further treatment or re-irradiation with chemotherapy. The study showed a DFS advantage, but no OS advantage. There were more deaths due to treatment in the treatment arm (5 vs 0)...
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