What adjuvant therapy would you offer for a cisplatin-eligible patient with upper tract urothelial carcinoma and Lynch Syndrome?

Topics: Genitourinary Cancers • Bladder Cancer • Medical Oncology

Would T or N group change your recommendation?

Answer from: Medical Oncologist at Academic Institution

Good question and discussed it with Dr. @Ali R. Khaki. We have seen data from the POUT phase 3 trial (Birtle et al., PMID 32145825) showing significant DFS benefit with adjuvant Gem/Cis vs observation after radical surgery (due to study closure the trial was not powered to show OS benefit) in patien...

Comments

Medical Oncologist at Alvin & Lois Lapidus Cancer Institute Northwest Hospital
It appears that in colon cancer and gastric cancer...

Medical Oncologist at University of Washington School of Medicine
Good question but probably not much due to the dif...

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