What adjuvant treatment approach would you choose for a premenopausal woman with lymph node positive poorly differentiated metaplastic breast cancer that is ER low+, PR+, HER2 negative?
Is there a role for KEYNOTE-522 since ER + metaplastic breast cancer have similar behavior to triple negative metaplastic breast cancer?
1 Answer
Mednet MemberInvited Expert
Medical Oncology · Harvard Medical School
Answered on
Given the tumor is ER low+ (and I'm going to assume not strongly PR+ in this case since that would be highly unusual in the setting of ER low positivity only...but please comment back if I'm wrong!), yes, I would consider this biologically triple-negative disease (and very high risk given metaplasti...
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